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20 Best Pain Medication For Toothache (2022 Updated)

There are a number of pain medications that can be used to help relieve toothache pain. These include over-the-counter medications such as ibuprofen and aspirin, as well as prescription medications such as codeine and tramadol.

In some cases, your dentist may also recommend using a topical pain reliever such as lidocaine. If your toothache pain is severe, your dentist may also recommend that you have a root canal procedure to help relieve the pain.

20 Best Pain Medication For Toothache

Product Image Product Name Features Price

Dentek Instant Pain Relief, Advanced Kit

  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums

Red Cross Complete Medication Kit, Toothache – 0.125 fl oz

  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits

Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz

  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth

Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz

  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits

Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz

  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.

Orajel Toothache Pain Relief Gel, Maximum Strength – 0.25 oz tube

  • Relieves minor toothache pain
  • Easy-to-use gel formula simplifies application
  • Contains benzocaine

Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz

  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application

Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube

  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.

Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply

Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz

  • 0.41 oz

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
Dentek Instant Pain Relief, Advanced Kit
  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums
Red Cross Complete Medication Kit, Toothache – 0.125 fl oz
  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits
Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz
  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth
Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz
  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits
Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz
  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.
Orajel Toothache Pain Relief Gel, Maximum Strength – 0.25 oz tube
  • Relieves minor toothache pain
  • Easy-to-use gel formula simplifies application
  • Contains benzocaine
Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz
  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application
Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube
  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.
Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore
  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply
Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz
  • 0.41 oz
Orajel Dental Gel 5.3g Rapid Toothache Relief
  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache

1. Dentek Instant Pain Relief, Advanced Kit

Dentek Instant Pain Relief, Advanced Kit

  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums
  • Its mint flavor offers a fresh feel upon application

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Product Details

Specifications

Details
Area of Application Gums
Number of Applicators 50
Recommended Age Group Adult
Disposable Yes
Gender Unisex

2. Red Cross Complete Medication Kit, Toothache – 0.125 fl oz

Red Cross Complete Medication Kit, Toothache - 0.125 fl oz

  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits
  • Ingredients
  • Special Note

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Specifications

Details
Units in Package 1
Unit Size 0.125 fl oz
Indications Temporarily relieves throbbing, persistent toothache due to a cavity until a dentist can be seen.
Directions Rinse tooth with water to remove any food particles from the cavity. Using tweezers immerse cotton pellet in medication. To prevent dripping, squeeze gently between fingers to remove excess liquid. Place pellet in tooth cavity for one minute without touching surrounding tissues, then remove. Supervise children using this product. Adults and Children 12 Years and Over: Use to 4 times daily or as directed by a dentist or doctor. Children Under 12 Years: Ask a dentist or doctor.
Ingredients Active Ingredient: Eugenol (85%). Inactive Ingredient: Sesame Oil.

3. Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz

Orajel 4X Severe Toothache Oral Pain Reliever Cream - 0.33 oz

  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth
  • Get relief from toothaches and gum pain with the mineral oil extracts

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Specifications

Details
Units in Package 1
Unit Size 0.33 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums. First aid to help prevent infection in minor oral irritation.
Directions Adults and Children 2 Years of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor up to 4 times daily or as directed by a dentist or doctor. Children Under 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 Years of Age: Do not use.
Ingredients Active Ingredients: Benzalkonium Chloride (0.1%), Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Antiseptic, Oral Pain Reliever, Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, PEG-8, PEG-75, PEG/PPG 116/66 Copolymer, Poloxamer 407, Sodium Saccharin, Sorbic Acid, Titanium Dioxide, Water.

4. Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz

Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid - 0.45 fl oz

  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits
  • Ingredients
  • Special Note

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Details
Units in Package 1
Unit Size 0.45 fl oz
Indications Uses: For the temporary relief of pain due to canker sores; minor injury of the mouth and gums; minor irritation of the mouth and gums caused by dentures.
Directions Directions: Remove imprinted safety seal from bottle cap. Adults and Children 2 Years of Age and Over: Apply product with cotton swab or finger to the affected area. Use up to 4 times daily or as directed by a physician or healthcare provider. Children Under 12 Years of Age: Should be supervised in the use of this product. Children Under 2 Years of Age: Ask a physician or healthcare provider.
Ingredients Active Ingredients: Benzocaine (20%), Menthol (0.1%). Purpose: Oral Pain Reliever, Oral Pain Reliever. Inactive Ingredients: Alcohol (54.5% by Volume), Flavor, Polyethylene Glycol, Red 40, Sodium Saccharin, Water, Yellow 5.

5. Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz

Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream - 0.25 oz

  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.
  • Instant Pain Relief.
  • Long-Lasting Cream.

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.25 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums. First aid to help prevent infection in minor oral irritation.
Directions Adults and Children 2 Years of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor. Children Between 2 and 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 Years of Age: Do not use.
Ingredients Active Ingredients: Benzalkonium Chloride (0.13%), Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Pain Reliever, Oral Pain Reliever, Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Chamomile, Flavor, PEG-8, PEG-75, PEG/PPG 116/66 Copolymer, Poloxamer 407, Sodium Saccharin, Sorbic Acid, Titanium Dioxide, Water.

6. Orajel Toothache Pain Relief Gel, Maximum Strength – 0.25 oz tube

Orajel Toothache Pain Relief Gel, Maximum Strength - 0.25 oz tube

  • Relieves minor toothache pain
  • Easy-to-use gel formula simplifies application
  • Contains benzocaine
  • For use as a temporary expedient until dentist is consulted

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Specifications

Details
Units in Package 1
Unit Size 0.25 oz
Indications Uses: For the temporary relief of pain due to toothaches. To help protect against infection in minor oral irritation.
Directions Directions: Cut open tip of tube on score mark. Adults and Children 2 Years of Age and Over: Apply a small amount to product to the cavity and around gum surrounding the teeth. Use up to 4 times daily or as directed by a physician or healthcare provider. Children Under 12 Years of Age: Should be supervised in the use of this product. Children Under 2 Years of Age: Ask a physician or healthcare provider.
Ingredients Active Ingredients: Benzocaine (20%), Benzalkonium Chloride (0.1%). Purpose: Oral Pain Reliever, Antiseptic. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, Polyethylene Glycol, Sodium Saccharin, Sorbic Acid.

7. Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz

Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength - 0.25 oz

  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application
  • Orajel toothache gel goes right to the source of the pain for instant relief
  • For the temporary relief of pain due to toothaches

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.25 oz
Indications Temporarily relieves pain due to toothaches.
Directions Do not use if tube tip is cut prior to opening. Cut open tip of tube on score mark. Adults and children 2 years and older: Apply a small amount of product to the cavity and around gum surrounding the teeth. Use up to 4 times daily or as directed by a dentist or doctor. Children under 12 years: Should be supervised in the use of this product. Children under 2 years: Ask a dentist or doctor.
Ingredients Active Ingredient: Benzocaine (10%). Inactive Ingredients: Flavor, Polyethylene Glycol, Sodium Saccharin, Sorbic Acid.

8. Orajel Instant Pain Relief, Fast-Acting Gel – 0.125 oz

Orajel Instant Pain Relief, Fast-Acting Gel - 0.125 oz

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.125 oz
Indications Uses: For the temporary relief of pain due to toothaches. To help protect against infection in minor oral irritation.
Directions Directions: Cut open tip of tube on score mark. Adults and Children 2 Years of Age and Over: Apply a small amount of product to the cavity and around gum surrounding the teeth. Use up to 4 times daily or as directed by a physician or healthcare provider. Children Under 12 Years of Age: Should be supervised in the use of this product. Children Under 2 Years of Age: Ask a physician or healthcare provider.
Ingredients Active Ingredients: Benzocaine (20%), Benzalkonium Chloride (0.1%). Purpose: Oral Pain Reliever, Antiseptic. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, Polyethylene Glycol, Sodium Saccharin, Sorbic Acid.

9. Pack of 1 Orajel 4X Medicated for Toothache & Gum Relief, Cooling Gel, 0.25 oz

Pack of 1 Orajel 4X Medicated for Toothache & Gum Relief, Cooling Gel, 0.25 oz

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10. Benzodent Dental Pain Relieving Cream Topical Anesthetic 1 Ounce Tube

Benzodent Dental Pain Relieving Cream Topical Anesthetic 1 Ounce Tube

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Product Details

Specifications

Details
Active Ingredients Benzocaine
Item Form Cream
Age Range (Description) 2 years +
Dimensions 1 Ă— 1.06 Ă— 1.13 in

11. Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube

Orajel Maximum Double Relief Toothache Gel - 0.42 oz tube

  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.
  • Do not use continuously.
  • Instant pain relief.
  • No. 1 pharmacist recommended for toothache relief.

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Specifications

Details
Units in Package 1
Unit Size 0.42 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums.
Directions Adult and Children 2 Year of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor. Children Between 2 and 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 years of Age: Do not use.
Ingredients Active Ingredients: Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, PEG-8, PEG-75, Sodium Saccharin, Sorbic Acid, Water.

12. Orajel Severe Toothache & Gum Relief Plus Triple Medicated Gel

Orajel Severe Toothache & Gum Relief Plus Triple Medicated Gel

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13. Red Cross Toothache Medication Drops

Red Cross Toothache Medication Drops

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Details
Assembled Product Weight 0.8 lb

14. Orajel 4X Medicated for Toothache & Gum Cream – 0.33oz

Orajel 4X Medicated for Toothache & Gum Cream - 0.33oz

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15. Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply

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Product Details

Specifications

Details
Product Type Pain reliever
Product Form Gel
Container Type Tube
Recommended Age Group Adult, children

16. Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz

Anbesol Pain Relief, Instant, Maximum Strength, Liquid - 0.41 fl oz

  • 0.41 oz

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Specifications

Details
Units in Package 1
Unit Size 0.41 fl oz
Indications Uses: Temporarily relieves pain associated with the following mouth and gum irritations: toothache; sore gums; canker sores; braces; minor dental procedures; dentures..
Directions General directions: See new warnings information. Do not use if plastic blister or backing material is broken or if backing material is separated from plastic. Read and keep card for complete warnings and information. Age group directions: Adults and Children 2 Years of Age and Older:: Wipe liquid on with cotton, or cotton swab, or fingertip. Apply to the affected area up to 4 times daily or as directed by a doctor/dentist. Children Under 12 Years of Age:: Adult supervision should be given in the use of this product. Children Under 2 Years of Age:: Do not use.
Ingredients Active Ingredients: Benzocaine (20 ). Purpose: Oral anesthetic. Inactive Ingredients: Benzyl Alcohol, D&C Yellow 10, FD&C Blue 1, FD&C Red 40, Methylparaben, Natural Flavor, Polyethylene Glycol, Polysorbate 80, Propylene Glycol, Saccharin

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17. 6 Pack – Orajel Severe Pain Formula 0.33 oz

6 Pack - Orajel Severe Pain Formula 0.33 oz

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18. Equate 4X Medicated Toothache & Gum Relief Oral Pain Gel, 0.25 oz

Equate 4X Medicated Toothache & Gum Relief Oral Pain Gel, 0.25 oz

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19. Orajel Dental Gel 5.3g Rapid Toothache Relief

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
  • Suitable for adults and children 12 years and above

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20. Orajel Dental Gel for Toothache – 5.3g

Orajel Dental Gel for Toothache - 5.3g

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Conclusion

There are a variety of pain medications available for toothaches, and the best one for you will depend on the severity of your pain and any other medical conditions you may have. Over-the-counter pain relievers like ibuprofen or acetaminophen can be effective for mild to moderate pain.

If your pain is more severe, your dentist may prescribe a stronger pain medication, such as codeine or hydrocodone. In some cases, your dentist may also recommend a local anesthetic to numb the area around your tooth.

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